Alumis is advancing a late-stage portfolio of next-generation targeted therapies for immune-mediated diseases, designed to optimize impact and transform patient care - helping millions worldwide live healthier, fuller lives.
Leadership Team
Martin Babler
President, Chief Executive Officer and Chairman of the Board
Martin Babler is the President, Chief Executive Officer and Chairman of the Board at Alumis, Inc. Prior to Alumis, he served as President and CEO of Principia Biopharma, until its acquisition by Sanofi in October 2020. Prior to Principia Biopharma, Martin served as President and CEO of Talima Therapeutics from 2007 to 2011. From 1998 to 2007, he held several positions at Genentech, most notably as Vice President, Immunology Sales and Marketing. While at Genentech, he also helped to build and lead the Commercial Development organization and led the Cardiovascular Marketing organization. Martin previously served at Eli Lilly and Company in positions focused on sales, sales management, global marketing, and business development. Martin serves on the Board of Directors of Prelude Therapeutics Inc., 89bio and the Emerging Companies Section Governing Board of the Biotechnology Innovation Organization. Martin received a Swiss Federal Diploma in Pharmacy from the Federal Institute of Technology in Zurich and completed the Executive Development Program at the Kellogg Graduate School of Management at Northwestern University.
Mark Bradley
Chief Development Officer
Mark Bradley joined in March 2021 as our Chief Development Officer. He brings 30 years of experience in the biotechnology industry. Before joining Alumis he was Senior Vice President (SVP) and South San Francisco Site Head at MyoKardia following that company’s acquisition by Bristol Myers Squibb (BMS), and SVP and Project Team Leader for CAMZYOS® prior to the acquisition. Before MyoKardia, Mark held various roles at Biomarin and Genentech, most recently serving as Head, Business Management, gRED Clinical Operations. Mark began his career at UCSF in public health research and received his B.A. and M.A. from the University of California, Berkeley.
Kolbot By, Ph.D.
SVP, Head of Technical Operations
Kolbot By joined in January of 2022 as Senior Vice President of Technical Operations. He has more than 20 years of experience in the biopharmaceutical industry, overseeing manufacturing processes of new chemical entities, and advancing development programs from proof of concept to commercial production. Prior to Alumis, Kolbot was SVP, Technical Operations at Rain Therapeutics where he led the company’s late-stage CMC development program. Prior to Rain Therapeutics, Kolbot was Vice President, Chemical Development at Principia Biopharma where he led the company’s late-stage drug substance program. Prior to Principia Biopharma he was at Corvus Pharmaceuticals, Onyx Pharmaceuticals, Aryx Therapeutics, and NPS Pharmaceuticals. While at Onyx, Kolbot helped to develop the carfilzomib drug substance program from Phase 2 through commercialization. Kolbot holds a B.S. in chemistry from UC Santa Barbara and a Ph.D. in chemistry from UC Davis.
Jack Danilkowicz
Chief Commercial Officer
Jack Danilkowicz joined Alumis in 2025 and is Chief Commercial Officer. Before joining Alumis, Jack worked at Amgen serving as Senior Vice President, Commercial Strategy and General Manager, Ophthalmology, where he was responsible for driving the commercial strategy for Amgen’s rare disease portfolio and leading the sales and marketing efforts for its ophthalmology business. Prior to Amgen’s 2023 acquisition of Horizon Therapeutics, Mr. Danilkowicz spent over a decade at Horizon, where he held several leadership roles in business development, strategy and sales & marketing. He played a pivotal role in the company’s transformation into a leader in rare disease therapies, including overseeing the successful launch of the blockbuster medicine TEPEZZA®. During his tenure, Horizon's annual net product sales increased from approximately $300 million to nearly $4 billion. Mr. Danilkowicz holds a Master of Business Administration from the Kellogg School of Management at Northwestern University, a Master of Education and Bachelor of Science in Commerce from the University of Virginia.
Jörn Drappa M.D., Ph.D.
Chief Medical Officer
Jörn Drappa, MD, Ph.D. joined in August 2022 as our Chief Medical Officer (CMO). He is a board-certified rheumatologist with over 25 years of experience in developing novel treatments for autoimmune and inflammatory diseases. Most recently, he served as CMO at Ventyx Biosciences. Prior to Ventyx Biosciences, Dr. Drappa co-founded Viela Bio, a biotechnology company focused on the discovery, development and commercialization of treatments for autoimmune and severe inflammatory diseases serving as its Head of R&D and CMO until its acquisition by Horizon Therapeutics in March 2021. At Viela Bio, Dr. Drappa led the development of UPLIZNA® (inebilizumab-cdon) in multiple indications, culminating in its approval for the treatment of Neuromyelitis Optica Spectrum Disorder (NMOSD). Prior to Viela Bio, he held various roles of increasing responsibility leading clinical development programs at MedImmune/AstraZeneca, Genentech, and Amgen. Dr. Drappa received his medical and Ph.D. degrees from the University of Cologne in Germany. He completed a residency in internal medicine at New York Presbyterian Hospital and a fellowship in rheumatology at the Hospital for Special Surgery, NY.
David M Goldstein, Ph.D.
Chief Scientific Officer
David Goldstein, Ph.D. joined in September 2021 as our Chief Scientific Officer (CSO). He is a recognized expert in the fields of small molecule drug discovery, kinase inhibitor design and covalent technologies. David has more than 25 years of industrial experience and has led teams that advanced several small molecule drug candidates into clinical trials in immune-mediated diseases including tolebrutinib, rilzabrutinib, atuzabrutinib and pamapimod. He is a named inventor on more than 40 patents, and he has authored more than 40 scientific publications. Most recently, David was the CSO at Principia Biopharma, a company he helped to launch in 2011 and take public in 2018. Prior to joining Principia, David held positions of increasing responsibility at Roche including Head of Inflammation Chemistry. David serves on the Board member of Frontier Medicines in South San Francisco. He received his Ph.D. in Chemistry at the University of Virginia and completed postdoctoral studies in organic chemistry at the University of Pittsburgh.
Grace Halteh
SVP, Head of Quality and Regulatory
Grace joined in September 2022. She currently serves as Senior Vice President, Head of Quality and Regulatory. She brings over 25 years of experience in life sciences quality & compliance, operations excellence, and project management. As a quality professional, Grace has recognized expertise in quality management & compliance, inspection readiness, vendor management programs, clinical study execution, and due diligence initiatives. She helped lead Global Health Authority inspections, resulting in the successful registration of multiple Biologics and small molecule products. Grace brings strong leadership and end to end vision across various GxP quality functions encompassing establishment of quality management departments, conducting operational assessments, implementing process improvements, and building quality systems. Prior to joining Alumis, Grace was the VP of Quality at Arcellx and a member of the Executive Management team. She held various quality and operations leadership roles at Exelixis, Nektar Therapeutics, Jazz Pharmaceuticals, Genentech, Janssen - A Johnson and Johnson Company, Elan Pharmaceuticals and Syntex. Grace holds an M.S. in Systems Management, and a B.S in Cell and Molecular Biology.
Roy Hardiman
Chief Business and Strategy Officer
Roy Hardiman is currently Alumis' Chief Business and Strategy Officer. He joined in September 2021 as our Chief Business and Legal Officer. He has over 30 years of business development, legal, alliance management and strategic experience in the biopharmaceutical field. Before joining Alumis, he was Chief Business Officer of Principia Biopharma where he negotiated the company’s core collaborations with Sanofi and AbbVie. Roy spent almost two decades at Genentech where he was one of the company’s lead negotiators, accountable for the alliance and legal aspects of the company’s relationship with Roche. Prior to joining Genentech, Roy was an attorney with Morrison & Foerster LLP. Roy received his B.A. in pharmacology and M.A. in biology (biochemistry/molecular biology emphasis) from University of California, Santa Barbara, and his JD from University of California, Los Angeles School of Law, and serves on the Board of Trustees of the University of California, Santa Barbara Foundation.
Claire Langrish, Ph.D.
SVP, Head of Immunology and Translational Science
Claire joined in September of 2021. She currently serves as Senior Vice President, Head of Immunology and Translational Science. She is a recognized leader in the field of immunology, with a focus on drug discovery in immune mediated diseases. Claire previously served as Vice President, Head of Immunology and Biology at Principia Biopharma, where she championed target biology, preclinical and clinical translation, building novel insights and deeper understanding of BTK beyond the B cell. Prior to Principia Biopharma, she held positions of increasing responsibility at DNAX, Roche, Takeda and Theravance. During her postdoctoral studies, Claire was credited with the discovery of Th17 cells, and uncovered the key role of IL-23 and IL-17 in autoimmunity, prompting rewritten text-books and a new wave of approved medicines for patients. Claire received a B.S. in Biochemistry from Imperial College London, and a Ph.D. in Immunology from Great Ormond Street Institute of Child Health, University College London, UK.
Sanam Pangali
Chief Legal Officer and Corporate Secretary
Sanam Pangali is the Chief Legal Officer and Corporate Secretary of Alumis. She joined the company in September 2024 as Senior Vice President, Legal, and was promoted to her current role in July 2025. Prior to Alumis, Sanam held several leadership roles at ACELYRIN, Inc., most recently serving as Chief Legal Officer and Head of People. She brings broad in-house experience across the biopharma, technology, and renewable energy sectors, including roles as General Counsel at Snapdocs, Inc. and Senior Director & Associate General Counsel at Principia Biopharma Inc. Sanam began her legal career in the Business & Finance practice groups at Morrison & Foerster LLP. She earned her J.D. from the University of Pennsylvania Carey Law School and holds a B.A. in Political Science, with a minor in Economics, from the University of California, San Diego.
John Schroer
Chief Financial Officer
John Schroer joined in May 2022 as our Chief Financial Officer (CFO). He brings more than 30 years of biopharmaceutical development and investing experience in the life sciences industry. In his role at Alumis, John is responsible for leading Finance, Corporate Communications, Facilities, and Information Technology. Prior to Alumis, John served as the CFO for ArsenalBio Inc. Previously, John was CFO of Translate Bio (acquired by Sanofi). Earlier in his career, John held Portfolio Manager and Senior Analyst roles managing investment teams and portfolios across the life sciences industry, most recently with Allianz Global Investors. Previously, John was with Schroer Capital, HealthCor Management, ITROS Capital, INVESCO Funds Group and TCW Group. John serves on the board of Azitra. He received his B.S. in History and International Relations from the University of Wisconsin-Madison, and his M.B.A from the University of Wisconsin-Madison School of Business. John is also a CFA® charterholder.
Board of Directors
Srinivas Akkaraju, M.D., Ph.D.
Founder and Managing Member, Samsara BioCapital
Managing Director, AyurMaya, an affiliate of Matrix Capital Management
President and CEO, Chairman of the Board
Alan B. Colowick, M.D., M.P.H.
Independent Board Member
Independent Board Member
Founder and CEO, Foresite Capital
Independent Board Member
CEO, ArriVent Biopharma
Srinivas Akkaraju, M.D., Ph.D.
Srinivas Akkaraju, M.D., Ph.D. has served as a member of our Board since March 2024. Dr. Akkaraju is a founder and managing member of Samsara BioCapital, a venture capital firm, a position he has held since March 2017. From April 2013 to February 2016, Dr. Akkaraju served as a general partner of Sofinnova Ventures, a venture capital firm. From January 2009 to April 2013, Dr. Akkaraju served as managing director of New Leaf Venture Partners, a venture capital firm. Dr. Akkaraju presently serves on the board of directors of vTv Therapeutics Inc., Scholar Rock Holding Corporation, Mineralys Therapeutics, Inc., Inventiva S.A. and Syros Pharmaceuticals, Inc., and numerous private biopharmaceutical companies. During the past five years, he served as a director of Chinook Therapeutics, Inc., Jiya Acquisition Corp., Aravive, Inc. (formerly Versartis, Inc.), Intercept Pharmaceuticals, Inc., Principia Biopharma Inc., and Seagen, Inc. Dr. Akkaraju received an M.D. and a Ph.D. in Immunology from Stanford University and undergraduate degrees in Biochemistry and Computer Science from Rice University.
Sapna Srivastava, Ph.D.
Sapna Srivastava, Ph.D. has served as a member of our Board since August 2022. From March 2021 to October 2021, Dr. Srivastava served as the interim Chief Financial Officer at eGenesis, Inc., a biopharmaceutical company. From September 2017 to January 2019, Dr. Srivastava served as the Chief Financial and Strategy Officer at Abide Therapeutics, Inc., a biopharmaceutical company acquired by H. Lundbeck A/S in 2019. From April 2015 to December 2016, Dr. Srivastava served as the Chief Financial and Strategy Officer at Intellia Therapeutics, Inc., a gene editing company. Previously, for nearly 15 years, Dr. Srivastava was a senior biotechnology analyst at Goldman Sachs, Morgan Stanley, and ThinkEquity Partners, LLC. Dr. Srivastava began her career as a research associate at JP Morgan. Dr. Srivastava currently serves on the board of directors of the following public biopharmaceutical companies: Tourmaline Bio, Inc., Aura Biosciences, Inc., Innoviva, Inc. and Nuvalent, Inc. Dr. Srivastava holds a Ph.D. from New York University School of Medicine and a B.Sc. from St. Xavier’s College, University of Bombay.
Martin Babler
Martin Babler is the President, Chief Executive Officer and Chairman of the Board at Alumis, Inc. Prior to Alumis, he served as President and CEO of Principia Biopharma, until its acquisition by Sanofi in October 2020. Prior to Principia Biopharma, Martin served as President and CEO of Talima Therapeutics from 2007 to 2011. From 1998 to 2007, he held several positions at Genentech, most notably as Vice President, Immunology Sales and Marketing. While at Genentech, he also helped to build and lead the Commercial Development organization and led the Cardiovascular Marketing organization. Martin previously served at Eli Lilly and Company in positions focused on sales, sales management, global marketing, and business development. Martin serves on the Board of Directors of Prelude Therapeutics Inc., Sardona Therapeutics, 89bio and the Emerging Companies Section Governing Board of the Biotechnology Innovation Organization. Martin received a Swiss Federal Diploma in Pharmacy from the Federal Institute of Technology in Zurich and completed the Executive Development Program at the Kellogg Graduate School of Management at Northwestern University.
Alan B. Colowick, M.D., M.P.H.
Alan B. Colowick, M.D., M.P.H. has served as a member of our Board since January 2022. Since April 2021, Dr. Colowick has served as the Senior Managing Director of Matrix Capital Management Company. From May 2017 to January 2021, Dr. Colowick served as a private equity partner at Sofinnova Ventures. From 2010 to 2017, Dr. Colowick held various positions at Celgene Corporation, a pharmaceutical company, including Executive Vice President. From 2008 to 2010, Dr. Colowick was the Chief Executive Officer at Gloucester Pharmaceuticals, Inc., a pharmaceutical company, until its acquisition by Celgene in 2010. From 2006 to 2008, Dr. Colowick was President of Oncology for Geron Corporation, a biotechnology company, and from 2005 to 2006 was Chief Medical Officer of Threshold Pharmaceuticals, a pharmaceutical company. From 1999 to 2005, Dr. Colowick held various positions at Amgen Inc., a biopharmaceutical company. Dr. Colowick currently serves as a member on the board of directors of multiple private companies and previously served as a member on the board of directors of ACELYRIN, Inc. from November 2021 to May 2025. Dr. Colowick completed specialty training in Hematology- Oncology at the Dana Farber Cancer Institute/Brigham and Women’s Hospital. Dr. Colowick received a M.D. from Stanford University, a M.P.H from Harvard University, and a B.S. in Molecular Biology from the University of Colorado.
Patrick Machado, J.D.
Patrick Machado, J.D. has served as a member of our Board since June 2024. Mr. Machado was a co- founder of Medivation, Inc., a biopharmaceutical company, and served as its chief business officer from December 2009 to April 2014 and as its chief financial officer from December 2004 until his retirement in March 2014. From 1998 to 2001, Mr. Machado worked with ProDuct Health, Inc., a medical device company, as senior vice president, chief financial officer and earlier as general counsel. Upon ProDuct Health Inc.’s acquisition by Cytyc Corporation, a diagnostic and medical device company, he served as a consultant to Cytyc Corporation to assist with transitional matters from 2001 to 2002. Earlier in his career, Mr. Machado worked for Morrison & Foerster LLP, an international law firm, and for the Massachusetts Supreme Judicial Court. Mr. Machado serves as chair of the board of directors of Adverum Biotechnologies, Inc., and as a member of the boards of directors of Arcus Biosciences, Inc. and Xenon Pharmaceuticals, Inc., both of which are publicly traded biopharmaceutical companies. Mr. Machado also chairs the board of directors of Prota Therapeutics, and is a member of the board of directors of Avenzo Therapeutics, both of which are privately held biopharmaceutical companies. Mr. Machado previously served on the board of directors of public traded companies, such as ACELYRIN, Inc. from April 2021 to May 2025, Chimerix, Inc. from June 2014 to June 2024, Turnstone Biologics Inc. from August 2018 to April 2024, Turning Point Therapeutics, Inc. from May 2019 to September 2022, Endocyte, Inc. from February 2018 to December 2018, Axovant Sciences, Inc. from June 2017 to February 2018, SCYNEXIS, Inc. from September 2015 to June 2019, Medivation, Inc. from April 2014 to September 2016; Inotek Pharmaceuticals Corporation (now Rocket Pharmaceuticals, Inc.) from August 2016 to January 2018 and Principia Biopharma Inc. from June 2019 to September 2020; and on the board of directors of privately held companies such as Roivant Sciences, Ltd. from October 2016 to June 2022, and Therachon AG from January 2019 to July 2019. Mr. Machado received a J.D. from Harvard Law School and a B.A. in German and a B.S. in Economics from Santa Clara University.
James B. Tananbaum, M.D.
James B. Tananbaum, M.D. has served as a member of our Board since May 2021. Dr. Tananbaum is currently the President, Chief Executive Officer and a director of Foresite Capital Management, a U.S.- focused healthcare investment firm, which he founded in 2010. From 2000 to 2010, Dr. Tananbaum served as Co-Founder and Managing Director of Prospect Venture Partners L.P. II and III, healthcare venture partnerships. Dr. Tananbaum was also the Founder of GelTex, Inc. in 1991, an intestinal medicine pharmaceutical company acquired by Sanofi-Genzyme, and Theravance, Inc. in 1997 (now Theravance Biopharma, Inc., a diversified biopharmaceutical company focused on organ-selective medicines, and Innoviva, Inc., a respiratory-focused healthcare asset management company partnered with Glaxo Group Limited). Dr. Tananbaum presently serves on the board of directors of Fabric Genomics, Inc., among other companies. During the past five years, Dr. Tananbaum served on the boards of directors of Quantum-SI Incorporate, Gemini Therapeutics, Inc., 10X Genomics, Inc., and Kinnate Biopharma Inc., among other companies. Dr. Tananbaum received an M.D. and an M.B.A. from Harvard University, and a B.S. and a B.S.E.E. from Yale University in Applied Math and Computer Science.
Lynn Tetrault, J.D.
Lynn Tetrault, J.D. has served as a member of our Board since May 2025. Ms. Tetrault currently serves as the Chair of the board of directors of NeoGenomics, Inc., and has been a member of its board of directors since 2015. Ms. Tetrault has also served as a member of the board of directors of Rhythm Pharmaceuticals, Inc., a publicly traded biopharmaceutical company, since 2020 and previously served as a member of the board of directors of ACELYRIN, Inc. from December 2023 until May 2025. Previously, Ms. Tetrault served in a variety of executive roles at AstraZeneca PLC from 1993 to 2014 including most recently as Executive Vice President of Human Resources and Corporate Affairs from 2007 to 2014. Ms. Tetrault has a B.A. from Princeton University and a J.D. from the University of Virginia Law School.
Zhengbin (Bing) Yao, Ph.D.
Zhengbin (Bing) Yao, Ph.D. has served as a member of our Board since June 2021. From May 2021 to the present, Dr. Yao served as the Chief Executive Officer and chairman of the board of directors of ArriVent Biopharma, a biotechnology company. From March 2018 to March 2021, Dr. Yao served as the Chief Executive Officer, President, and from January 2019 to March 2021 also as chairman of the board of directors of Viela Bio, Inc., a biotechnology company, until it was acquired by Horizon Therapeutics in March 2021. From October 2010 to February 2018, Dr. Yao served as Senior Vice President, Head of Respiratory, Inflammation, Autoimmune iMED at MedImmune, the biologics division of AstraZeneca plc and from October 2015 to February 2018 also as Senior Vice President, Head of Immuno-Oncology Franchise. From March 2008 to September 2010, Dr. Yao served as Head of PTL for Immunology, Infectious Diseases, Neuroscience, and Metabolic Disease at Genentech, Inc., a biopharmaceutical company. From October 2000 to September 2007, Dr. Yao held various leadership roles at Tanox Inc., a biopharmaceutical company, and was Vice President and Head of Research before it was acquired by Genentech, Inc. in 2007. Dr. Yao currently serves on the board of directors of Visen Pharmaceuticals, a biopharmaceutical company, and Nikang Therapeutics, Inc., a biotechnology company. Dr. Yao received his Ph.D. in Microbiology and Immunology from the University of Iowa and M.S. in Immunology from Anhui Medical University in Anhui, China.